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Differences in Metabolism of Vinylidene Chloride Between Mice and Rats

✍ Scribed by Jones, B K; Hathway, D E

Book ID
109833850
Publisher
Nature Publishing Group
Year
1978
Tongue
English
Weight
980 KB
Volume
37
Category
Article
ISSN
0007-0920

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## Abstract Hepatotoxicity of vinylidene chloride (1,1‐dichloroethylene, VDC) in rats was evidenced by increases of serum enzyme activities of the aminotransferases (GOT, GPT) and sorbitol dehydrogenase (SDH). Simultaneous treatment with ethanol (4.8 g kg^βˆ’1^ p.o.) totally inhibited these hepatotox