Metabolism of 1,3-butadiene to 1,2-epoxybutene-3 in rats follows saturation kinetics. Comparative investigation of inhalation pharmacokinetics in mice also revealed a saturation pattern. For both species "linear" pharmacokinetics apply at exposure concentrations below 1000 ppm 1,3-butadiene; saturat
Investigation of species differences in isobutene (2-methylpropene) metabolism between mice and rats
✍ Scribed by G. A. Csanády; D. Freise; B. Denk; J. G. Filser; M. Cornet; V. Rogiers; R. J. Laib
- Publisher
- Springer-Verlag
- Year
- 1991
- Tongue
- English
- Weight
- 515 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0340-5761
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