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Differences in Dihydropyrimidine Dehydrogenase Activities Between Gastric and Colorectal Cancer

โœ Scribed by Bunzo Nakata; Kazuya Muguruma; Shigehito Yamagata; Kiyotaka Yukimoto; Kiyoshi Maeda; Yukio Nishiguchi; Masaichi Ohira; Yasuyuki Kato; Kosei Hirakawa


Book ID
111578799
Publisher
Springer US
Year
2004
Tongue
English
Weight
417 KB
Volume
49
Category
Article
ISSN
0163-2116

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## Abstract Thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) are important enzymes of DNA __de novo__ synthesis and the salvage pathway in cancer cells, respectively. Intratumoral TS and DPD gene expressions were evaluated to determine the correlation between the expression of th