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Thymidine phosphorylase and dihydropyrimidine dehydrogenase activity in colorectal carcinoma and patients prognosis

โœ Scribed by Ikeguchi, Masahide; Makino, Masato; Kaibara, Nobuaki


Book ID
113041709
Publisher
Springer
Year
2002
Tongue
English
Weight
162 KB
Volume
387
Category
Article
ISSN
1435-2451

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Thymidine phosphorylase and dihydropyrim
โœ Elaina S.R. Collie-Duguid; Stephen J. Johnston; Linda Boyce; Nicola Smith; Aaron ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 96 KB

It is essential for actively proliferating cells to increase their rate of DNA synthesis to progress through the cell cycle. This is reflected in the increased uracil usage that is a common feature in solid tumours. Thymidine phosphorylase (TP) anabolises formation of pyrimidine nucleosides availabl