Thymidine phosphorylase and dihydropyrim
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Elaina S.R. Collie-Duguid; Stephen J. Johnston; Linda Boyce; Nicola Smith; Aaron
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Article
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2001
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John Wiley and Sons
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French
โ 96 KB
It is essential for actively proliferating cells to increase their rate of DNA synthesis to progress through the cell cycle. This is reflected in the increased uracil usage that is a common feature in solid tumours. Thymidine phosphorylase (TP) anabolises formation of pyrimidine nucleosides availabl