Chlorotrimethylsilane -sodium iodide reagent (in situ generation of iodotrimethylsilane)in acetonitrile reduces alkyl and aryl/aroyl azides to the corresponding amines/amides in excellent yields under neutral and mild conditions.
Diethyl Chlorophosphite: A Mild Reagent for Efficient Reduction of Nitro Compounds to Amines
โ Scribed by Fischer, Bilha; Sheihet, Larisa
- Book ID
- 120265846
- Publisher
- American Chemical Society
- Year
- 1998
- Tongue
- English
- Weight
- 57 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0022-3263
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Iodotrimethylsilane: A Mild and Efficient Reagent for the Reduction of Azides to Amines. -An efficient and chemoselective protocol for the reduction of azides using in situ prepared iodotrimethylsilane as a reducing agent is reported. The corresponding amines are formed in excellent yields. -
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