## Abstract Variants in the amino acid composition of the primary antibodyβbinding site of hepatitis B surface antigen (HBsAg) have been identified in a number of populations with chronic hepatitis B virus (HBV) infection. Direct sequencing of amplified or cloned PCR products, solid phase detection
Diagnostic impact of the genetic variability of the hepatitis B virus surface antigen gene
β Scribed by Bernard Weber
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 118 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0146-6615
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## Abstract Sera from 20 Chinese patients with chronic hepatitis B were examined for hepatitis B e antigen and hepatitis B virus (HBV) DNA. There was considerable discordance with HBV DNA not being detectable in 10 out of 13 (77%) patients who were hepatitis B e antigen positive. Further testing fo