𝔖 Bobbio Scriptorium
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The absence of hepatitis B virus DNA in hepatitis B e antigen positive sera from chronic hepatitis B surface antigen carriers in China

✍ Scribed by Janet S. Scott; Pei-En Pan; Raymond A. Pace; Theo P. Sloots; Prof. W. Graham Cooksley

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
413 KB
Volume
30
Category
Article
ISSN
0146-6615

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✦ Synopsis

Abstract

Sera from 20 Chinese patients with chronic hepatitis B were examined for hepatitis B e antigen and hepatitis B virus (HBV) DNA. There was considerable discordance with HBV DNA not being detectable in 10 out of 13 (77%) patients who were hepatitis B e antigen positive. Further testing for anti‐HBe and HBV‐DNA polymerase activity confirmed the results. Possible reasons for this discordance are discussed but neither hepatitis D (delta) infection nor the acquired immunodeficiency syndrome (AIDS) could be implicated.

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