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Development of an On-Line Liquid Chromatography-Electrospray Tandem Mass Spectrometry Assay to Quantitatively Determine 1, N 2 -Etheno-2‘-deoxyguanosine in DNA

✍ Scribed by Loureiro, Ana Paula M.; Marques, Sabrina A.; Garcia, Camila C. M.; Di Mascio, Paolo; Medeiros, Marisa H. G.

Book ID
127201438
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
167 KB
Volume
15
Category
Article
ISSN
0893-228X

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## Abstract High‐performance liquid chromatography (HPLC) was combined with electrospray ionization tandem mass spectrometry (ESI‐MS/MS) to develop a sensitive and selective method for the quantitative measurement of __N__^7^‐(2‐hydroxyethyl)guanine (__N__^7^‐HEG) adducts in DNA obtained from ethyl