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Detection and Quantitation of Acrolein-Derived 1, N 2 -Propanodeoxyguanosine Adducts in Human Lung by Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry

✍ Scribed by Zhang, Siyi; Villalta, Peter W.; Wang, Mingyao; Hecht, Stephen S.

Book ID
125935985
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
112 KB
Volume
20
Category
Article
ISSN
0893-228X

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## Abstract High‐performance liquid chromatography (HPLC) was combined with electrospray ionization tandem mass spectrometry (ESI‐MS/MS) to develop a sensitive and selective method for the quantitative measurement of __N__^7^‐(2‐hydroxyethyl)guanine (__N__^7^‐HEG) adducts in DNA obtained from ethyl