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Analysis of Crotonaldehyde- and Acetaldehyde-Derived 1, N 2 -Propanodeoxyguanosine Adducts in DNA from Human Tissues Using Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry

โœ Scribed by Zhang, Siyi; Villalta, Peter W.; Wang, Mingyao; Hecht, Stephen S.


Book ID
127022746
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
136 KB
Volume
19
Category
Article
ISSN
0893-228X

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## Abstract Highโ€performance liquid chromatography (HPLC) was combined with electrospray ionization tandem mass spectrometry (ESIโ€MS/MS) to develop a sensitive and selective method for the quantitative measurement of __N__^7^โ€(2โ€hydroxyethyl)guanine (__N__^7^โ€HEG) adducts in DNA obtained from ethyl