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Development of a New Method to Measure Sphingosine-1-phosphate in Tumor Interstitial Fuid by Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry

✍ Scribed by Nagahashi, M.; Allegood, J.; Yamada, A.; Aoyagi, T.; Huang, W.; Miyazaki, H.; Milstein, S.; Spiegel, S.; Takabe, K.

Book ID
122416785
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
64 KB
Volume
179
Category
Article
ISSN
0022-4804

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Highly sensitive method for the determin
Highly sensitive method for the determination of omeprazole in human plasma by liquid chromatography–electrospray ionization tandem mass spectrometry: application to a clinical pharmacokinetic study
✍ Shivva Vittal; Ramesh Ganneboina; Buddhadev Layek; Ravi Kumar Trivedi; Kishore K 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 705 KB

## Abstract A highly sensitive, rapid assay method has been developed and validated for the estimation of omeprazole (OPZ) in human plasma with liquid chromatography coupled to tandem mass spectrometry with electrospray ionization in the positive‐ion mode. The assay procedure involves alkalinizatio