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Development and validation method for determination of fluoxetine and its main metabolite norfluoxetine by nonaqueous capillary electrophoresis in human urine

✍ Scribed by J. Rodríguez Flores; J.J. Berzas Nevado; G. Castañeda Peñalvo; N. Mora Diez

Book ID
111875335
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
135 KB
Volume
65
Category
Article
ISSN
0039-9140

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Development and validation method for determination of Paroxetine and its metabolites by nonaqueous capillary electrophoresis in human urine. Experimental design for evaluating the ruggedness of the method
✍ Juana Rodríguez Flores; Juan J. Barzas Nevado; Ana M. Contento Salcedo; Maria P. 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 153 KB 👁 2 views

## Abstract A simple, rapid, and sensitive procedure using nonaqueous capillary electrophoresis (NACE) to measure Paroxetine (one of the mostly used antidepressants for mental diseases treatment) and three metabolites has been developed and validated. Optimum separation of paroxetine and metabolite