## Determination of bupivacaine and three of its metabolites in rat urine by capillary electrophoresis A capillary electrophoretic (CE) method for the analysis of urinary extracts of the local anesthetic, bupivacaine, and its three main metabolites, desbutylbupivacaine, 3'-hydroxybupivacaine, and
Determination of theophylline and its metabolites in rat liver microsomes and human urine by capillary electrophoresis
โ Scribed by Zhi-Yi Zhang; Michael J. Fasco; Laurence S. Kaminsky
- Publisher
- Elsevier Science
- Year
- 1995
- Weight
- 507 KB
- Volume
- 665
- Category
- Article
- ISSN
- 0378-4347
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A method for the quantitation of three metabolites of theophylline, 1-methylxanthine (1MX), 3-methylxanthine (3MX), and 1,3 -dimethyluric acid (13DMU) in human liver microsomes has been developed. The method is based on a simple one-step extraction followed by isocratic, reversed-phase high-performa
A high performance liquid chromatographic (HPLC) technique for the determination of three metabolites of theophylline, 3-methylxanthine (3-MX), 1-methylxanthine (1-MX) and 1,3-dimethyluric acid (1,3-DMU) in human liver microsomes is described. The analytes were extracted from human liver microsomes