Development and validation method for determination of Paroxetine and its metabolites by nonaqueous capillary electrophoresis in human urine. Experimental design for evaluating the ruggedness of the method (vol. 25, issue 3, pp. 454-462)

Development and validation method for de

Development and validation method for determination of Paroxetine and its metabolites by nonaqueous capillary electrophoresis in human urine. Experimental design for evaluating the ruggedness of the method

✍ Juana Rodríguez Flores; Juan J. Barzas Nevado; Ana M. Contento Salcedo; Maria P. 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 153 KB 👁 2 views

## Abstract A simple, rapid, and sensitive procedure using nonaqueous capillary electrophoresis (NACE) to measure Paroxetine (one of the mostly used antidepressants for mental diseases treatment) and three metabolites has been developed and validated. Optimum separation of paroxetine and metabolite