Nonaqueous capillary electrophoresis method for the analysis of tamoxifen, imipramine and their main metabolites in urine
✍ Scribed by J. Rodríguez Flores; J.J. Berzas Nevado; A.M. Contento Salcedo; M.P. Cabello Díaz
- Book ID
- 116900739
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 213 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0039-9140
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## Abstract A simple, rapid, and sensitive procedure using nonaqueous capillary electrophoresis (NACE) to measure Paroxetine (one of the mostly used antidepressants for mental diseases treatment) and three metabolites has been developed and validated. Optimum separation of paroxetine and metabolite
of 25 kPa The column oven temperature was mantamed at 60 "C for 1 min after inlection and then programmed 12 "/min to 380 "C which was held for 15 m n The spht inlector was operated at 300 "C and the FID at 380 "C