✦ LIBER ✦

Development and utilization of a combined LC–UV and LC–MS/MS method for the simultaneous analysis of tegafur and 5-fluorouracil in human plasma to support a phase I clinical study of oral UFT®/leucovorin

✍ Scribed by Cody J. Peer; Terence J. McManus; Herbert I. Hurwitz; William P. Petros

Book ID: 113688736
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 399 KB
Volume: 898
Category: Article
ISSN: 1873-376X
DOI: 10.1016/j.jchromb.2012.04.010

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

LC–MS–MS Method for Simultaneous Analysi

LC–MS–MS Method for Simultaneous Analysis of Abacavir and Lamivudine in Human Plasma, and Its Application to a Bioequivalence Study

✍ Noel A. Gomes; Ashutosh M. Pudage; Santosh S. Joshi; Vikas V. Vaidya; Sagar A. P 📂 Article 📅 2008 🏛 Springer 🌐 English ⚖ 626 KB

Development of an SPE-LC–MS/MS method fo

Development of an SPE-LC–MS/MS method for simultaneous quantification of bosentan and its active metabolite hydroxybosentan in human plasma to support a bioequivalence study

✍ Jignesh M. Parekh; Dhaval K. Shah; Mallika Sanyal; Manish Yadav; Pranav S. Shriv 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 940 KB

Development and validation of a highly s

Development and validation of a highly sensitive LC-MS/MS method for simultaneous quantitation of ethionamide and ethionamide sulfoxide in human plasma: application to a human pharmacokinetic study

✍ Abhijeet Y. Deshpande; Sandip Gurav; Ravindra Punde; Vishal Zambre; Rahul Kulkar 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 882 KB

## Abstract A highly sensitive and specific LC‐MS/MS method has been developed for simultaneous quantification of ethionamide and ethionamide sulfoxide in human plasma (300 µL) using prothionamide as an internal standard (IS). Solid‐phase extraction was used to extract ethionamide, ethionamide sulf

Development and validation of a highly s

Development and validation of a highly sensitive LC-MS/MS method for simultaneous quantitation of nortriptyline and 10-hydroxynortriptyline in human plasma: application to a human pharmacokinetic study

✍ Kishore Kumar Hotha; L. K. Ravindranath; K. N. Jaya Veera; K. Kishore Kumar; Y. 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 599 KB

Development and validation of LC–MS/MS m

Development and validation of LC–MS/MS methods for the determination of mirabegron and its metabolites in human plasma and their application to a clinical pharmacokinetic study

✍ Raymond van Teijlingen; John Meijer; Shin Takusagawa; Marcel van Gelderen; Cas v 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 697 KB

Development and validation of a sensitiv

Development and validation of a sensitive LC-MS/MS method with electrospray ionization for quantitation of pramipexole in human plasma: application to a clinical pharmacokinetic study

✍ D. Vijaya Bharathi; Kishore Kumar Hotha; P. V. Vidya Sagar; S. Sirish Kumar; A. 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 396 KB 👁 2 views

## Abstract A highly sensitive and specific LC‐MS/MS method has been developed and validated for the estimation of pramipexole (PPX) with 500 µL human plasma using memantine as an internal standard (IS). The API‐4000 was operated under multiple‐reaction monitoring mode (MRM) using the electrospray