𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Development and validation of LC–MS/MS methods for the determination of mirabegron and its metabolites in human plasma and their application to a clinical pharmacokinetic study

✍ Scribed by Raymond van Teijlingen; John Meijer; Shin Takusagawa; Marcel van Gelderen; Cas van den Beld; Takashi Usui


Book ID
116620716
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
697 KB
Volume
887-888
Category
Article
ISSN
1873-376X

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Validated LC–MS/MS method for quantifica
✍ Satish R. Patil; Ketan K. Nerurkar; Ashok M. Kalamkar; Vishwas Pukale; Kiran V. 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 196 KB 👁 2 views

An analytical method based on liquid–liquid extraction has been developed and validated for analysis of agomelatine in human plasma. Fluoxetine was used as an internal standard for agomelatine. A Betasil C18 (4.0 × 100 mm, 5 µm) column provided chromatographic separation of analytes followed by dete