✦ LIBER ✦

Development and therapeutic impact of HDAC6-selective inhibitors

✍ Scribed by Sabrina Dallavalle; Claudio Pisano; Franco Zunino

Book ID: 119194809
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 822 KB
Volume: 84
Category: Article
ISSN: 0006-2952
DOI: 10.1016/j.bcp.2012.06.014

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Inhibitors selective for HDAC6 in enzyme

Inhibitors selective for HDAC6 in enzymes and cells

✍ Praveer K. Gupta; Robert C. Reid; Ligong Liu; Andrew J. Lucke; Steve A. Broomfie 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 412 KB

Histone deacetylase inhibitors with anticancer or anti-inflammatory activity bind to Class I or Class I and II HDAC enzymes. Here we compare selectivity of inhibitors of a Class II HDAC enzyme (HDAC6) and find one that retains high selectivity in macrophages.

Pyridylalanine-Containing Hydroxamic Aci

Pyridylalanine-Containing Hydroxamic Acids as Selective HDAC6 Inhibitors

✍ Stefan Schäfer; Laura Saunders; Sonja Schlimme; Vassil Valkov; Julia M. Wagner; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 741 KB

Enhancing the apoptotic and therapeutic

Enhancing the apoptotic and therapeutic effects of HDAC inhibitors

✍ Ailsa J. Frew; Ricky W. Johnstone; Jessica E. Bolden 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 272 KB

Discovery and Development of Novel HDAC

Discovery and Development of Novel HDAC Inhibitors for Huntington’s Disease

✍ H. Patzke; R. Chesworth; Z. Li; G. Rahil; J. Wang; J. Smith; F.L. Huet; G. Shapi 📂 Article 📅 2008 🏛 Springer-Verlag 🌐 English ⚖ 44 KB

Selective class II HDAC inhibitors impai

Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC–MEF2 complexes

✍ Nebbioso, Angela; Manzo, Fabio; Miceli, Marco; Conte, Mariarosaria; Manente, Luc 📂 Article 📅 2009 🏛 Nature Publishing Group 🌐 English ⚖ 750 KB

GSK3 inhibitors: development and therape

GSK3 inhibitors: development and therapeutic potential

✍ Cohen, Philip; Goedert, Michel 📂 Article 📅 2004 🏛 Nature Publishing Group 🌐 English ⚖ 269 KB