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GSK3 inhibitors: development and therapeutic potential

✍ Scribed by Cohen, Philip; Goedert, Michel


Book ID
109949519
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
269 KB
Volume
3
Category
Article
ISSN
1474-1776

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Bipolar disorder is a serious psychiatric condition that has been treated for over 50 years with lithium. Lithium is a well established glycogen synthase kinase-3 (GSK-3) inhibitor, suggesting that manipulating GSK-3 may have therapeutic value in treating bipolar disorder. GSK-3 is regulated by a wi