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Determination of the pyridinium metabolite derived from haloperidol in brain tissue, plasma and urine by high-performance liquid chromatography with fluorescence detection

โœ Scribed by Kazuo Igarashi; Neal Castagnoli Jr.

Publisher
Elsevier Science
Year
1992
Weight
592 KB
Volume
579
Category
Article
ISSN
0378-4347

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โœ Bilal Yilmaz; Ali Asci; Sakir Arslan ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 143 KB ๐Ÿ‘ 2 views

## Abstract A simple, specific and sensitive HPLC method has been developed for the determination of metoprolol in human plasma and urine. Separation of metoprolol and atenolol (internal standard) was achieved on an Ace C~18~ column (5โ€‰ฮผm, 250โ€‰mmร—4.6โ€‰mm id) using fluorescence detection with ฮป~ex~=2