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Determination of Elsamitrucin (BMY-28090) in plasma and urine by high-performance liquid chromatography with fluorescence detection

โœ Scribed by I. Klein; J. Welink; W.J.F. van der Vijgh


Publisher
Elsevier Science
Year
1993
Weight
368 KB
Volume
622
Category
Article
ISSN
0378-4347

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## Abstract A simple, specific and sensitive HPLC method has been developed for the determination of metoprolol in human plasma and urine. Separation of metoprolol and atenolol (internal standard) was achieved on an Ace C~18~ column (5โ€‰ฮผm, 250โ€‰mmร—4.6โ€‰mm id) using fluorescence detection with ฮป~ex~=2