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Determination of Point Mutational Spectra of Benzo[a]pyrene-diol Epoxide in Human Cells

✍ Scribed by Phouthone Keohavong and William G. Thilly

Book ID
124310904
Publisher
Environmental Health Information Service
Year
1992
Tongue
English
Weight
908 KB
Volume
98
Category
Article
ISSN
0091-6765

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## Abstract The frequency of cell transformation was determined after treatment of normal hamster embryo cells with benzo(a)pyrene (BP) and six of its metabolites. These metabolites included the __trans__ 4,5‐, 7,8‐ and 9,10‐dihydrodiols; the 4,5‐epoxide; and two stereoisomers of the non‐K‐region d