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Mutational spectra vary with exposure conditions: benzo[a]pyrene in human cells

✍ Scribed by Jia Chen; William G. Thilly

Book ID: 113194991
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 928 KB
Volume: 357
Category: Article
ISSN: 0027-5107
DOI: 10.1016/0027-5107(96)00107-8

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## Abstract Bronchial epithelial cells are often exposed to airborne mutagens that have the potential to induce genetic changes involved in the development of lung cancer. Although lung tumors often display alterations in the expression of oncogenes and/or tumor suppressor genes, the role of specif