Sulforaphane and its analogues inhibit C
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Katarzyna Skupinska; Irena Misiewicz-Krzeminska; Rafal Stypulkowski; Katarzyna L
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Article
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2009
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John Wiley and Sons
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English
β 380 KB
## Abstract CYP1A1 and CYP1A2 enzymes metabolize polycyclic aromatic hydrocarbons (PAHs) to the reactive oxyderivatives. PAHs can induce the activity of both enzymes, which increases its conversion and enhances risk of carcinogenesis. Thus, the inhibition of CYP enzymes is recognized as a cancer ch