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Determination of alendronate in low volumes of plasma by column-switching high-performance liquid chromatography method and its application to pharmacokinetic studies in human plasma

✍ Scribed by Eunmi Ban; Ji-Youn Park; Hyung Tae Kim; Chong-Kook Kim

Book ID
107642601
Publisher
Springer
Year
2011
Tongue
English
Weight
356 KB
Volume
34
Category
Article
ISSN
0253-6269

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## Abstract A simple, specific and sensitive HPLC method with UV detection was developed and validated for the determination of tectoridin in rat plasma for the first time. Chromatographic separation was performed on a Welchrom^TM^ C~18~ column (150 Γ— 4.6Β mm, i.d., 5Β Β΅m) at a flow rate of 1.0Β mLΒ mi