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Determination of cicletanine in human plasma by high-performance liquid chromatography using automated column switching

✍ Scribed by Susan M. Antoniewicz; Jack A. Cook; Richard R. Brown

Book ID
107997013
Publisher
Elsevier Science
Year
1992
Weight
320 KB
Volume
573
Category
Article
ISSN
0378-4347

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## Abstract Melagatran is an active thrombin inhibitor showing oral and parenteral bioavailability for antithrombotic therapy. A simple and convenient liquid chromatographic method has been developed and applied to the analysis of melagatran in rabbit plasma. The clean‐up and separation of the samp