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High-Performance Liquid Chromatography Determination of Acitretin in Plasma and Its Application to a Pharmacokinetic Study in Human Subjects

✍ Scribed by Christian Surber; Jean-Philippe Laugier; Jean-Marie Geiger; Hot Bun; Alain Durand; Howard I. Maibach

Book ID
110341631
Publisher
Springer US
Year
1992
Tongue
English
Weight
644 KB
Volume
09
Category
Article
ISSN
0724-8741

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## Abstract A simple, specific and sensitive HPLC method with UV detection was developed and validated for the determination of tectoridin in rat plasma for the first time. Chromatographic separation was performed on a Welchrom^TM^ C~18~ column (150 Γ— 4.6Β mm, i.d., 5Β Β΅m) at a flow rate of 1.0Β mLΒ mi