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Determination of a new atypical antipsychotic agent perospirone and its metabolite in human plasma by automated column-switching high-performance liquid chromatography

✍ Scribed by Norio Yasui-Furukori; Yoshimasa Inoue; Tomonori Tateishi


Book ID
108497448
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
163 KB
Volume
789
Category
Article
ISSN
1873-376X

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## Abstract Melagatran is an active thrombin inhibitor showing oral and parenteral bioavailability for antithrombotic therapy. A simple and convenient liquid chromatographic method has been developed and applied to the analysis of melagatran in rabbit plasma. The clean‐up and separation of the samp