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Determination of an antipsychotic agent (ICI 204,636) and its 7-hydroxy metabolite in human plasma by high-performance liquid chromatography and gas chromatography—mass spectrometry

✍ Scribed by Robert H. Pullen; Karen M. Palermo; Michael A. Curtis

Book ID: 107997010
Publisher: Elsevier Science
Year: 1992
Weight: 518 KB
Volume: 573
Category: Article
ISSN: 0378-4347
DOI: 10.1016/0378-4347(92)80473-4

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## Abstract Cyadox is a novel antimicrobial growth‐promoter of the quinoxalines. For food safety and pharmacokinetic studies, a convenient, sensitive and reproducible LC‐ESI‐MS/MS method was developed for the simultaneous determination of cyadox and its major metabolites, quinoxaline‐2‐carboxylic a