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Detection of the JAK2 V617F missense mutation by high resolution melting analysis and its validation

✍ Scribed by Tze-Kiong Er; Sheng-Fung Lin; Jan-Gowth Chang; Li-Ling Hsieh; Shu-Kai Lin; Li-Hsuan Wang; Chin-Wen Lin; Chao-Sung Chang; Ta-Chih Liu

Book ID
116348391
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
381 KB
Volume
408
Category
Article
ISSN
0009-8981

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## Abstract __Background__: Several methods have been established to detect the JAK2 V617F mutation, a frequent event involved in the pathogenesis of myeloproliferative neoplasms (MPNs). High‐resolution melt (HRM) analysis is a newly established technique without the requirement of any gel‐based po