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Rapid detection of JAK2 V617F mutation using high-resolution melting analysis with LightScanner platform

✍ Scribed by Jun Qian; Jiang Lin; Dong-Ming Yao; Qin Chen; Gao-Fei Xiao; Run-Bi Ji; Yun Li; Jing Yang; Zhen Qian

Book ID: 116348855
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 502 KB
Volume: 411
Category: Article
ISSN: 0009-8981
DOI: 10.1016/j.cca.2010.08.020

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## Abstract __Background__: Several methods have been established to detect the JAK2 V617F mutation, a frequent event involved in the pathogenesis of myeloproliferative neoplasms (MPNs). High‐resolution melt (HRM) analysis is a newly established technique without the requirement of any gel‐based po