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Sensitive Detection and Quantification of the JAK2V617F Allele by Real-Time PCR

✍ Scribed by Huijsmans, Cornelis J.J.; Poodt, Jeroen; Savelkoul, Paul H.M.; Hermans, Mirjam H.A.


Book ID
125426332
Publisher
American Society for Investigative Pathology
Year
2011
Tongue
English
Weight
784 KB
Volume
13
Category
Article
ISSN
1525-1578

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## Abstract Diagnosis of the myeloproliferative disorders, polycythemia vera (PV), essential thrombocythemia (ET) and idiopathic myelofibrosis (IMF) is difficult due to lack of diagnostic markers. Recently, the acquisition of a mutation in the Janus kinase 2 (__JAK2__) gene by hemopoietic cells has