## Abstract Nitric oxide (NO) is a shortโliving free molecule synthesized by three different isoforms of nitric oxide synthases (NOS)โneuronal NOS, endothelial NOS, and inducible NOSโassociated with neuromuscular transmission, muscle contractility, mitochondrial respiration, and carbohydrate metabo
Detection of nitric oxide and nitric oxide synthases in psoriasis
โ Scribed by A. D. Ormerod; R. Weller; P. Copeland; N. Benjamin; S. H. Ralston; P. Grabowksi; R. Herriot
- Publisher
- Springer-Verlag
- Year
- 1998
- Tongue
- English
- Weight
- 447 KB
- Volume
- 290
- Category
- Article
- ISSN
- 0340-3696
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## Abstract Nitric oxide (NO) is a biologically active inorganic molecule produced when the semiessential amino acid lโarginine is converted to lโcitrulline and NO via the enzyme nitric oxide synthase (NOS). NO is known to be involved in the regulation of many physiological processes, such as contr
It has been previously demonstrated that microglia and astrocytes produce micromolar amounts of nitric oxide in vitro. In this study, we demonstrate that primary rat oligodendrocytes can be stimulated to produce iNOS mRNA as detected by Northern blot and in situ hybridization analysis and a 131-kDa