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Role of nitric oxide and nitric oxide synthases in ischemia-reperfusion injury in rat organotypic hippocampus slice

✍ Scribed by Meng Xianfang; Shi Jing; Liu Xiaochun; Zhang Jing; Sun Ning


Publisher
Springer-Verlag
Year
2005
Tongue
Chinese
Weight
346 KB
Volume
25
Category
Article
ISSN
0510-9752

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We determined the functional role of nitric oxide (NO) and endothelins (ET), two potent vasoactive mediator systems in the liver, for the pathogenesis of sinusoidal perfusion failure and lethal hepatocyte injury after low-flow ischemia/reperfusion in the isolated perfused rat liver. NO synthase bloc