It has been previously demonstrated that microglia and astrocytes produce micromolar amounts of nitric oxide in vitro. In this study, we demonstrate that primary rat oligodendrocytes can be stimulated to produce iNOS mRNA as detected by Northern blot and in situ hybridization analysis and a 131-kDa
Nitric oxide production and nitric oxide synthase immunoreactivity inNaegleria fowleri
✍ Scribed by Saúl Rojas-Hernández; Marco A. Rodríguez-Monroy; Leticia Moreno-Fierros; Adriana Jarillo-Luna; Marisela Carrasco-Yepez; Angel Miliar-García; Rafael Campos-Rodríguez
- Publisher
- Springer-Verlag
- Year
- 2007
- Tongue
- English
- Weight
- 241 KB
- Volume
- 101
- Category
- Article
- ISSN
- 1432-1955
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## Abstract Nitric oxide (NO) is a biologically active inorganic molecule produced when the semiessential amino acid l‐arginine is converted to l‐citrulline and NO via the enzyme nitric oxide synthase (NOS). NO is known to be involved in the regulation of many physiological processes, such as contr
The overproduction or underproduction of nitric oxide has been implicated in pathological symptoms such as endotoxic shock, diabetes, allograft rejection, and myocardial ischimia/reperfusion injury. A thorough understanding of the biosynthesis of nitric oxide is necessary to probe and manipulate the