Detection of CSF-specific oligoclonal antibodies to recombinant JC virus VP1 in patients with progressive multifocal leukoencephalopathy
✍ Scribed by C.J.M Sindic; C Trebst; M.P Van Antwerpen; S Frye; W Enzensberger; G Hunsmann; W Lüke; T Weber
- Book ID
- 117337476
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 294 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0165-5728
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## Abstract Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system, which is thought to be a result of the reactivation of JC virus (JCV), a human polyomavirus. The disease occurs in individuals with immunosuppression and in recent years there has
## Abstract __JC virus__ (JCV) causes progressive multifocal leukoencephalopathy under conditions of immunosuppression, especially associated with HIV. Despite the high prevalence of HIV‐1 infection, few cases of progressive multifocal leukoencephalopathy have been reported and only a small number