## Abstract Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system, which is thought to be a result of the reactivation of JC virus (JCV), a human polyomavirus. The disease occurs in individuals with immunosuppression and in recent years there has
Detection of JC virus by anti-VP1 immunohistochemistry in brains with progressive multifocal leukoencephalopathy
✍ Scribed by Wolfram Jochum; Thomas Weber; Stefan Frye; Gerhard Hunsmann; Wolfgang Lüke; A. Aguzzi
- Publisher
- Springer-Verlag
- Year
- 1997
- Tongue
- English
- Weight
- 356 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0001-6322
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## Abstract Progressive multifocal leukoencephalopathy (PML), a demyelinating infectious disease caused by JC virus (JCV), occurs almost exclusively in immunocompromised patients usually with malignant diseases. We report here a Japanese female with follicular lymphoma who subsequently developed PM
## Abstract __JC virus__ (JCV) causes progressive multifocal leukoencephalopathy under conditions of immunosuppression, especially associated with HIV. Despite the high prevalence of HIV‐1 infection, few cases of progressive multifocal leukoencephalopathy have been reported and only a small number