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Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy

✍ Scribed by Day, Sam E; Kettunen, Mikko I; Gallagher, Ferdia A; Hu, De-En; Lerche, Mathilde; Wolber, Jan; Golman, Klaes; Ardenkjaer-Larsen, Jan Henrik; Brindle, Kevin M

Book ID
109933055
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
546 KB
Volume
13
Category
Article
ISSN
1078-8956

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## Abstract We show here that hyperpolarized [1‐^13^C]pyruvate can be used to detect treatment response in a glioma tumor model; a tumor type where detection of response with ^18^fluoro‐2‐deoxyglucose, using positron emission tomography, is limited by the high background signals from normal brain t