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217 Detecting tumor responses to treatment using magnetic resonance imaging and hyperpolarized spectroscopy

โœ Scribed by K.M. Brindle

Book ID
119599954
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
43 KB
Volume
7
Category
Article
ISSN
1359-6349

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Detecting tumor response to treatment us
Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy
โœ Day, Sam E; Kettunen, Mikko I; Gallagher, Ferdia A; Hu, De-En; Lerche, Mathilde; ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 546 KB

Measurements of early tumor responses to therapy have been shown, in some cases, to predict treatment outcome. We show in lymphoma-bearing mice injected intravenously with hyperpolarized [1-13 C]pyruvate that the lactate dehydrogenasecatalyzed flux of 13 C label between the carboxyl groups of pyruva