𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Tumor imaging using hyperpolarized 13C magnetic resonance spectroscopy

✍ Scribed by Kevin M. Brindle; Sarah E. Bohndiek; Ferdia A. Gallagher; Mikko I. Kettunen


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
800 KB
Volume
66
Category
Article
ISSN
0740-3194

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Detection of tumor glutamate metabolism
✍ Ferdia A. Gallagher; Mikko I. Kettunen; Sam E. Day; De-en Hu; Magnus Karlsson; A πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 274 KB πŸ‘ 1 views

## Abstract Dynamic nuclear polarization can be used to increase the sensitivity of solution state ^13^C magnetic resonance spectroscopy by four orders of magnitude. We show here that [1‐^13^C]glutamate can be polarized to 28%, representing a 35,000‐fold increase in its sensitivity to detection at

Detecting response of rat C6 glioma tumo
✍ Sam E. Day; Mikko I. Kettunen; Murali Krishna Cherukuri; James B. Mitchell; Mart πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 684 KB

## Abstract We show here that hyperpolarized [1‐^13^C]pyruvate can be used to detect treatment response in a glioma tumor model; a tumor type where detection of response with ^18^fluoro‐2‐deoxyglucose, using positron emission tomography, is limited by the high background signals from normal brain t

Accelerated spectroscopic imaging of hyp
✍ Arjun Arunachalam; David Whitt; Kenneth Fish; Randy Giaquinto; Joseph Piel; Rona πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 324 KB

## Abstract The ability to accelerate the spatial encoding process during a chemical shift imaging (CSI) scan of hyperpolarized compounds is demonstrated through parallel imaging. A hardware setup designed to simultaneously acquire ^13^C data from multiple receivers is presented here. A system cons

Hyperpolarized 13C magnetic resonance de
✍ Yann Jamin; Cristina Gabellieri; Lynette Smyth; Steven Reynolds; Simon P. Robins πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 348 KB

## Abstract Carboxypeptidase G2 (CPG2) is a bacterial enzyme that is currently employed in a range of targeted cancer chemotherapy strategies such as gene‐directed enzyme prodrug therapy (GDEPT). Employing dynamic nuclear polarization (DNP) and natural abundance ^13^C magnetic resonance spectroscop

In vivo measurement of ethanol metabolis
✍ Daniel M. Spielman; Dirk Mayer; Yi-Fen Yen; James Tropp; Ralph E. Hurd; Adolf Pf πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 574 KB

## Abstract [1‐^13^C]Pyruvate is a readily polarizable substrate that has been the subject of numerous magnetic resonance spectroscopy (MRS) studies of in vivo metabolism. In this work ^13^C‐MRS of hyperpolarized [1‐^13^C]pyruvate was used to interrogate a metabolic pathway involved in neither aero