Accelerated spectroscopic imaging of hyperpolarized C-13 pyruvate using SENSE parallel imaging

✍ Scribed by Arjun Arunachalam; David Whitt; Kenneth Fish; Randy Giaquinto; Joseph Piel; Ronald Watkins; Ileana Hancu

• Publisher: John Wiley and Sons
• Year: 2009
• Tongue: English
• Weight: 324 KB
• Volume: 22
• Category: Article
• ISSN: 0952-3480
• DOI: 10.1002/nbm.1401

✦ Synopsis

Abstract

The ability to accelerate the spatial encoding process during a chemical shift imaging (CSI) scan of hyperpolarized compounds is demonstrated through parallel imaging. A hardware setup designed to simultaneously acquire ^13^C data from multiple receivers is presented here. A system consisting of four preamplifiers, four gain stages, a transmit coil, and a four receive channel rat coil was built for single channel excitation and simultaneous multi‐channel detection of ^13^C signals. The hardware setup was integrated with commercial scanner electronics, allowing the system to function similar to a conventional proton multi‐channel setup, except at a different frequency. The ability to perform parallel imaging is demonstrated in vivo. CSI data from the accelerated scans are reconstructed using a self‐calibrated multi‐spectral parallel imaging algorithm, by using lower resolution coil sensitivity maps obtained from the central region of k‐space. The advantages and disadvantages of parallel imaging in the context of imaging hyperpolarized compounds are discussed. Copyright © 2009 John Wiley & Sons, Ltd.