𝔖 Bobbio Scriptorium
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Imaging tumour cell metabolism using hyperpolarized 13C magnetic resonance spectroscopy

✍ Scribed by Witney, Timothy H.; Brindle, Kevin M.

Book ID
120059306
Publisher
Portland Press
Year
2010
Tongue
English
Weight
222 KB
Volume
38
Category
Article
ISSN
0300-5127

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Measurements of early tumor responses to therapy have been shown, in some cases, to predict treatment outcome. We show in lymphoma-bearing mice injected intravenously with hyperpolarized [1-13 C]pyruvate that the lactate dehydrogenasecatalyzed flux of 13 C label between the carboxyl groups of pyruva