Alcohol Analogues of the Antimalarial Artemisinin. -A series of the title compounds such as (VIII)-(XI) is synthesized and used in the preparation of derivatives such as (XIII). These products are potent antimalarials with up to 140% of the efficacy of the natural artemisinin. -(CUMMING,
✦ LIBER ✦
Design, Synthesis, Derivatization, and Structure−Activity Relationships of Simplified, Tricyclic, 1,2,4-Trioxane Alcohol Analogues of the Antimalarial Artemisinin
✍ Scribed by Cumming, Jared N.; Wang, Dasong; Park, Sheldon B.; Shapiro, Theresa A.; Posner, Gary H.
- Book ID
- 120084375
- Publisher
- American Chemical Society
- Year
- 1998
- Tongue
- English
- Weight
- 364 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0022-2623
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
ChemInform Abstract: Design, Synthesis,
✍
J. N. CUMMING; D. WANG; S. B. PARK; T. A. SHAPIRO; G. H. POSNER
📂
Article
📅
2010
🏛
John Wiley and Sons
⚖ 37 KB
👁 1 views
Synthesis, Structure, and Antimalarial A
✍
Charles W. Jefford; Javier A. Velarde; Gérald Bernardinelli; Dorothy H. Bray; Da
📂
Article
📅
1993
🏛
John Wiley and Sons
🌐
German
⚖ 831 KB
Two sets of tricyclic 1,2,4-trioxanes containing the ABC (10, 11) and ACD ring portions (21, 22, 32, 33, 37, and 38) of artemisinin (1) were synthesized by successive photo-oxygenation of appropriate enol-ether precursors to 1,2-dioxanes and inter-and intramolecular reaction with a carbonyl compound
Tricyclic analogues of artemisinin: synt
✍
Avery, Mitchell A.; Chong, Wesley K. M.; Bupp, James E.
📂
Article
📅
1990
🏛
The Royal Society of Chemistry
🌐
English
⚖ 299 KB
Structure−Activity Relationships of the
✍
Avery, Mitchell A.; Fan, Pingchen; Karle, Jean M.; Bonk, Jason D.; Miller, Rober
📂
Article
📅
1996
🏛
American Chemical Society
🌐
English
⚖ 709 KB
Mechanism-Based Design, Synthesis, and i
✍
Posner, Gary H.; Oh, Chang Ho; Wang, Dasong; Gerena, Lucia; Milhous, Wilbur K.;
📂
Article
📅
1994
🏛
American Chemical Society
🌐
English
⚖ 300 KB
Structure−Activity Relationships of the
✍
Avery, Mitchell A.; Muraleedharan, Kannoth M.; Desai, Prashant V.; Bandyopadhyay
📂
Article
📅
2003
🏛
American Chemical Society
🌐
English
⚖ 394 KB