Two sets of tricyclic 1,2,4-trioxanes containing the ABC (10, 11) and ACD ring portions (21, 22, 32, 33, 37, and 38) of artemisinin (1) were synthesized by successive photo-oxygenation of appropriate enol-ether precursors to 1,2-dioxanes and inter-and intramolecular reaction with a carbonyl compound
✦ LIBER ✦
Structure−Activity Relationships of the Antimalarial Agent Artemisinin. 3. Total Synthesis of (+)-13-Carbaartemisinin and Related Tetra- and Tricyclic Structures
✍ Scribed by Avery, Mitchell A.; Fan, Pingchen; Karle, Jean M.; Bonk, Jason D.; Miller, Robert; Goins, D. Keith
- Book ID
- 121363142
- Publisher
- American Chemical Society
- Year
- 1996
- Tongue
- English
- Weight
- 709 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0022-2623
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