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Design, synthesis and biological evaluation of antagonists of LHRH including substitutions with L-azetidine 2-2-carboxylic acid

✍ Scribed by J.-C. Xu; K. Folkers; C. Bowers; A. Ljungqvist; D.-M. Feng; W.A. Hook


Book ID
115844759
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
149 KB
Volume
46
Category
Article
ISSN
0010-7824

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Several cyclic homopeptides containing ~-azetidine-2-carhoxylic acid (Aze)-an imino acid homologous with proline but containing one less methylene group in its cyclic side chain-have been prepared. T h e peptides reported include cyclo(Aze)e, cyclo(Aze):$, and cyclo(Aze),j. T h e synthesis and spect