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Synthesis of new functionalized aziridine-2- and azetidine-3-carboxylic acid derivatives of potential interest for biological and foldameric applications

✍ Scribed by Asta Žukauskaitė; Sven Mangelinckx; Vida Buinauskaitė; Algirdas Šačkus; Norbert De Kimpe


Publisher
Springer
Year
2011
Tongue
English
Weight
508 KB
Volume
41
Category
Article
ISSN
0939-4451

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📜 SIMILAR VOLUMES


Chemistry of Aziridine Carboxylic Acids,
✍ Jähnisch, Klaus 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 426 KB

## Abstract Enantiomerically pure __cis__‐ and __trans__‐1__H__‐aziridine‐carboxylic acid derivatives 2a, b and 3a, b have been prepared by asymmetric Michael‐type addition of ammonia to chiral acrylates 1a, b with high __syn__ selectivity. The title compounds were obtained from the diols 8a, b by