Synthesis of tert-butyl (2R,3R)-2-cyano-3-formyl-aziridine-1-carboxylate — A new potential building block for amino alcohols and polyamines
✍ Scribed by Klaus Jähnisch
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 78 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Enantiomerically pure __cis__‐ and __trans__‐1__H__‐aziridine‐carboxylic acid derivatives 2a, b and 3a, b have been prepared by asymmetric Michael‐type addition of ammonia to chiral acrylates 1a, b with high __syn__ selectivity. The title compounds were obtained from the diols 8a, b by
The preparative separation of the enantiomers of the title compound, a versatile chiral building block for the synthesis of unnatural amino acid esters, by high performance liquid chromatography on a chiral stationary phase (CSP), is reported for the first time. The CSP consists of amylose-(3,5-dime
A new chiral derivation reagent was developed for chiral amines and 104, 3775 (1982).