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Synthesis and biological evaluation of substituted 2,2'-oxybis(propionic acid) derivatives and related compounds

✍ Scribed by Bennett, Gregory B.; Houlihan, William J.; Mason, Robert B.; Engstrom, Robert G.


Book ID
126145698
Publisher
American Chemical Society
Year
1976
Tongue
English
Weight
636 KB
Volume
19
Category
Article
ISSN
0022-2623

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Epiceanothic acid (1) is a naturally occurring, but very rare pentacyclic triterpene with a unique pentacyclic triterpene (PT) structure. An efficient synthesis of 1 starting from betulin (3) has been accomplished in 12-steps with a total yield of 10% in our study. Compound 1 and selected synthetic