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Design of specific antagonists of the fibrinogen receptor

✍ Scribed by Hervé Minoux; Nicolas Moitessier; Yves Chapleur; Bernard Maigret


Book ID
105576166
Publisher
Springer Netherlands
Year
1997
Tongue
English
Weight
247 KB
Volume
4
Category
Article
ISSN
1573-3149

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RGD-peptidomimetics are currently being investigated as a class of potential antithrombotics that antagonize the fibrinogen receptor, GP IIb/IIIa, on the surface of platelets. These mimetics are expected to have decisive advantages -such as higher activity and specificity, oral bioavailability and l