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2. Flow cytometric characterization of GPIIb/IIIa specific inhibition of platelet aggregation by fibrinogen receptor-antagonists

✍ Scribed by S. Barlage; K. Wittig; G. Rothe; G. Schmitz


Book ID
114201617
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
130 KB
Volume
10
Category
Article
ISSN
0268-9499

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Quantitative detection of platelet GPIIb
✍ Lisa J. Green; Philip Marder; Suzane L. Um; Joseph A. Jakubowski; Jeffry B. Lawr πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 66 KB πŸ‘ 2 views

Platelet-membrane surface receptors are important targets for pharmacologic intervention in cardiovascular disease. Among these, glycoprotein (GP) IIb-IIIa is dominant and integrally involved in platelet aggregation and thrombus formation. When activated, GPIIb-IIIa binds soluble fibrinogen (Fb) in