Quantitative detection of platelet GPIIb
β
Lisa J. Green; Philip Marder; Suzane L. Um; Joseph A. Jakubowski; Jeffry B. Lawr
π
Article
π
1998
π
John Wiley and Sons
π
English
β 66 KB
π 2 views
Platelet-membrane surface receptors are important targets for pharmacologic intervention in cardiovascular disease. Among these, glycoprotein (GP) IIb-IIIa is dominant and integrally involved in platelet aggregation and thrombus formation. When activated, GPIIb-IIIa binds soluble fibrinogen (Fb) in